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The interaction between E3 ubiquitin ligase Parkin and mitophagy receptor PHB2 links inner mitochondrial membrane ubiquitination to efficient mitophagy

The autophagic clearance of mitochondria has been defined as mitophagy, which is triggered by mitochondrial damage and serves as a major pathway for mitochondrial homeostasis and cellular quality control. PINK1 and Parkin-mediated mitophagy is the most extensively studied form of mitophagy, which ha...

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Detalles Bibliográficos
Autores principales: Sun, Shan, Hou, Hongyu, Ma, Guoqiang, Ma, Qilian, Li, Ningning, Zhang, Li, Dong, Chunsheng, Cao, Mian, Tam, Kin Yip, Ying, Zheng, Wang, Hongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763867/
https://www.ncbi.nlm.nih.gov/pubmed/36379251
http://dx.doi.org/10.1016/j.jbc.2022.102704