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Upregulation of MiRNA-149-5p Reduces the Infract Volume in Middle Cerebral Artery Occlusion Rats by Modulating Cation-Chloride Cotransporters Expressions

INTRODUCTION: Brain ischemia often leads to the chloride gradient alternations, which affects volume regulation and neuronal survival. Increase in NKCC1 expression and reduction in KCC2 level under ischemic condition results in inflammation and neuronal death. In this study, we investigated the effe...

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Detalles Bibliográficos
Autores principales: Mostafavi, Hossein, Amoli, Narges, Ghasemloo, Elham, Forouzandeh, Meysam, Hosseini, Masoumeh, Eskandari, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute of Iran 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763874/
https://www.ncbi.nlm.nih.gov/pubmed/35871268
http://dx.doi.org/10.52547/ibj.3759