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BAFF blockade attenuates acute graft-versus-host disease directly via the dual regulation of T- and B-cell homeostasis

INTRODUCTION: B-cell-activating factor (BAFF) is associated with donor-specific antibodies and chronic graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (allo-HSCT). However, the effects of BAFF on T-cell physiological function have not been fully elucidated i...

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Detalles Bibliográficos
Autores principales: Jeon, Youngwoo, Lim, Jung-Yeon, Im, Keon-Il, Kim, Nayoun, Cho, Seok-Goo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763883/
https://www.ncbi.nlm.nih.gov/pubmed/36561743
http://dx.doi.org/10.3389/fimmu.2022.995149