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Production and immunogenicity of a deoxyribonucleic acid Alphavirus vaccine expressing classical swine fever virus E2-Erns protein and porcine Circovirus Cap-Rep protein

Classical swine fever virus (CSFV) and porcine Circovirus type 2 (PCV2) are economically pivotal infectious disease viruses of swine. Alphaviral RNA replicon plasmids have been used as an important vector for constructing nucleic acid vaccines. Here, we aimed to construct a recombinant alphaviral pl...

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Detalles Bibliográficos
Autores principales: Du, Fuyu, Cao, Zhi, Ye, Zixuan, He, Jun, Zhang, Weijie, Zhang, Ke, Ning, Pengbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764008/
https://www.ncbi.nlm.nih.gov/pubmed/36560936
http://dx.doi.org/10.3389/fmicb.2022.1065532