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Seeing spermine blocking of K(+) ion movement through inward rectifier Kir2.2 channels
Inwardly rectifier potassium (Kir) channels are a major potassium channel sub-class whose function is regulated by ligand-dependent gating and highly voltage-dependent block by polyamines. With molecular dynamics simulations over previously unattainable timescales, Jogini et al. (J. Gen. Physiol. ht...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764022/ https://www.ncbi.nlm.nih.gov/pubmed/36524992 http://dx.doi.org/10.1085/jgp.202213144 |