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Repurposing of berbamine hydrochloride to inhibit Ebola virus by targeting viral glycoprotein

Ebola virus (EBOV) infection leads to staggeringly high mortality rate. Effective and low-cost treatments are urgently needed to control frequent EBOV outbreaks in Africa. In this study, we report that a natural compound called berbamine hydrochloride strongly inhibits EBOV replication in vitro and...

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Detalles Bibliográficos
Autores principales: Yi, Dongrong, Li, Quanjie, Wang, Han, Lv, Kai, Ma, Ling, Wang, Yujia, Wang, Jing, Zhang, Yongxin, Liu, Mingliang, Li, Xiaoyu, Qi, Jianxun, Shi, Yi, Gao, George F., Cen, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764067/
https://www.ncbi.nlm.nih.gov/pubmed/36561997
http://dx.doi.org/10.1016/j.apsb.2022.05.023