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Spatio-temporal delivery of both intra- and extracellular toll-like receptor agonists for enhancing antigen-specific immune responses

For cancer immunotherapy, triggering toll-like receptors (TLRs) in dendritic cells (DCs) can potentiate antigen-based immune responses. Nevertheless, to generate robust and long-lived immune responses, a well-designed nanovaccine should consider different locations of TLRs on DCs and co-deliver both...

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Detalles Bibliográficos
Autores principales: Wang, Nannan, Zuo, Yueyue, Wu, Shengjie, Huang, Chenlu, Zhang, Linhua, Zhu, Dunwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764069/
https://www.ncbi.nlm.nih.gov/pubmed/36561992
http://dx.doi.org/10.1016/j.apsb.2022.05.032