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Novel phthalimides regulating PD-1/PD-L1 interaction as potential immunotherapy agents

Programmed cell death 1(PD-1)/programmed cell death ligand 1(PD-L1) have emerged as one of the most promising immune checkpoint targets for cancer immunotherapy. Despite the inherent advantages of small-molecule inhibitors over antibodies, the discovery of small-molecule inhibitors has fallen behind...

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Detalles Bibliográficos
Autores principales: Sun, Chengliang, Cheng, Yao, Liu, Xiaojia, Wang, Gefei, Min, Wenjian, Wang, Xiao, Yuan, Kai, Hou, Yi, Li, Jiaxing, Zhang, Haolin, Dong, Haojie, Wang, Liping, Lou, Chenguang, Sun, Yanze, Yu, Xinmiao, Deng, Hongbin, Xiao, Yibei, Yang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764071/
https://www.ncbi.nlm.nih.gov/pubmed/36561991
http://dx.doi.org/10.1016/j.apsb.2022.04.007