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Harnessing the cyclization strategy for new drug discovery

The design of new ligands with high affinity and specificity against the targets of interest has been a central focus in drug discovery. As one of the most commonly used methods in drug discovery, the cyclization represents a feasible strategy to identify new lead compounds by increasing structural...

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Detalles Bibliográficos
Autores principales: Tang, Kai, Wang, Shu, Gao, Wenshuo, Song, Yihui, Yu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764076/
https://www.ncbi.nlm.nih.gov/pubmed/36562004
http://dx.doi.org/10.1016/j.apsb.2022.09.022