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TGFβ(+) small extracellular vesicles from head and neck squamous cell carcinoma cells reprogram macrophages towards a pro‐angiogenic phenotype

Transforming growth factor β (TGFβ) is a major component of tumor‐derived small extracellular vesicles (TEX) in cancer patients. Mechanisms utilized by TGFβ(+) TEX to promote tumor growth and pro‐tumor activities in the tumor microenvironment (TME) are largely unknown. TEX produced by head and neck...

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Detalles Bibliográficos
Autores principales: Ludwig, Nils, Yerneni, Saigopalakrishna S., Azambuja, Juliana H., Pietrowska, Monika, Widłak, Piotr, Hinck, Cynthia S., Głuszko, Alicja, Szczepański, Mirosław J., Kärmer, Teresa, Kallinger, Isabella, Schulz, Daniela, Bauer, Richard J., Spanier, Gerrit, Spoerl, Steffen, Meier, Johannes K., Ettl, Tobias, Razzo, Beatrice M., Reichert, Torsten E., Hinck, Andrew P., Whiteside, Theresa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764108/
https://www.ncbi.nlm.nih.gov/pubmed/36537293
http://dx.doi.org/10.1002/jev2.12294