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Injectable bioorthogonal hydrogel (BIOGEL) accelerates tissue regeneration in degenerated intervertebral discs

Intervertebral disc (IVD) degeneration is a leading cause of back pain and precursor to more severe conditions, including disc herniation and spinal stenosis. While traditional growth factor therapies (e.g., TGFβ) are effective at transiently reversing degenerated disc by stimulation of matrix synth...

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Detalles Bibliográficos
Autores principales: Luo, Jeffrey, Darai, Anjani, Pongkulapa, Thanapat, Conley, Brian, Yang, Letao, Han, Inbo, Lee, Ki-Bum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764133/
https://www.ncbi.nlm.nih.gov/pubmed/36582500
http://dx.doi.org/10.1016/j.bioactmat.2022.11.017