Quantitative affinity measurement of small molecule ligand binding to major histocompatibility complex class-I–related protein 1 MR1

The Major Histocompatibility Complex class I–related protein 1 (MR1) presents small molecule metabolites, drugs, and drug-like molecules that are recognized by MR1-reactive T cells. While we have an understanding of how antigens bind to MR1 and upregulate MR1 cell surface expression, a quantitative,...

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Detalles Bibliográficos
Autores principales: Wang, Carl J.H., Awad, Wael, Liu, Ligong, Mak, Jeffrey Y.W., Veerapen, Natacha, Illing, Patricia T., Purcell, Anthony W., Eckle, Sidonia B.G., McCluskey, James, Besra, Gurdyal S., Fairlie, David P., Rossjohn, Jamie, Le Nours, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764189/
https://www.ncbi.nlm.nih.gov/pubmed/36403855
http://dx.doi.org/10.1016/j.jbc.2022.102714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764189/
https://www.ncbi.nlm.nih.gov/pubmed/36403855
http://dx.doi.org/10.1016/j.jbc.2022.102714

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