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Fitness Landscape-Guided Engineering of Locally Supercharged Virus-like Particles with Enhanced Cell Uptake Properties

[Image: see text] Protein-based nanoparticles are useful models for the study of self-assembly and attractive candidates for drug delivery. Virus-like particles (VLPs) are especially promising platforms for expanding the repertoire of therapeutics that can be delivered effectively as they can delive...

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Detalles Bibliográficos
Autores principales: Pistono, Paige E., Huang, Paul, Brauer, Daniel D., Francis, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764284/
https://www.ncbi.nlm.nih.gov/pubmed/36378277
http://dx.doi.org/10.1021/acschembio.2c00318