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Multivalent Fucosides Targeting β-Propeller Lectins from Lung Pathogens with Promising Anti-Adhesive Properties

[Image: see text] Fungal and bacterial pathogens causing lung infections often use lectins to mediate adhesion to glycoconjugates at the surface of host tissues. Given the rapid emergence of resistance to the treatments in current use, β-propeller lectins such as FleA from Aspergillus fumigatus, Sap...

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Detalles Bibliográficos
Autores principales: Duca, Margherita, Haksar, Diksha, van Neer, Jacq, Thies-Weesie, Dominique M.E., Martínez-Alarcón, Dania, de Cock, Hans, Varrot, Annabelle, Pieters, Roland J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764287/
https://www.ncbi.nlm.nih.gov/pubmed/36414265
http://dx.doi.org/10.1021/acschembio.2c00708