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Membrane Fusion Mediated by Non-covalent Binding of Re-engineered Cholera Toxin Assemblies to Glycolipids

[Image: see text] Membrane fusion is essential for the transport of macromolecules and viruses across membranes. While glycan-binding proteins (lectins) often initiate cellular adhesion, subsequent fusion events require additional protein machinery. No mechanism for membrane fusion arising from simp...

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Detalles Bibliográficos
Autores principales: Wehrum, Sarah, Siukstaite, Lina, Williamson, Daniel J., Branson, Thomas R., Sych, Taras, Madl, Josef, Wildsmith, Gemma C., Dai, Wenyue, Kempmann, Erik, Ross, James F., Thomsen, Maren, Webb, Michael E., Römer, Winfried, Turnbull, W. Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764410/
https://www.ncbi.nlm.nih.gov/pubmed/36367814
http://dx.doi.org/10.1021/acssynbio.2c00266