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Pyrimidine Nucleosides Syntheses by Late-Stage Base Heterocyclization Reactions

[Image: see text] An efficient two-step procedure for the syntheses of pyrimidine nucleosides is presented. A series of glycosyl 5-(aminomethylene)-1,3-dioxane-4,6-dione derivatives were prepared from β-anomeric isonitriles by reaction with Meldrum’s acid or by allowing aminomethylene Meldrum’s acid...

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Detalles Bibliográficos
Autores principales: Cavalli, Elfie S., Mies, Thomas, Rzepa, Henry S., White, Andrew J. P., Parsons, Philip J., Barrett, Anthony G.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764413/
https://www.ncbi.nlm.nih.gov/pubmed/36331529
http://dx.doi.org/10.1021/acs.orglett.2c03152