Aerobic Oxidative N-Heterocyclic Carbene-Catalyzed Formal [3+3] Cyclization for the Synthesis of Tetrasubstituted Benzene Derivatives

[Image: see text] Herein, we present an accessible aerobic N-heterocyclic carbene (NHC)-catalyzed method that efficiently produces tetrasubstituted benzene rings in a single reaction. The method employs atmospheric oxygen (O(2)) as the terminal oxidant in a reaction that requires two oxidative steps...

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Detalles Bibliográficos
Autores principales: Bacaicoa, Sara, Goossens, Ellymay, Sundén, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764416/
https://www.ncbi.nlm.nih.gov/pubmed/36469618
http://dx.doi.org/10.1021/acs.orglett.2c03879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764416/
https://www.ncbi.nlm.nih.gov/pubmed/36469618
http://dx.doi.org/10.1021/acs.orglett.2c03879

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