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Developmental phenomics suggests that H3K4 monomethylation confers multi-level phenotypic robustness
How histone modifications affect animal development remains difficult to ascertain. Despite the prevalence of histone 3 lysine 4 monomethylation (H3K4me1) on enhancers, hypomethylation appears to have minor effects on phenotype and viability. Here, we genetically reduce H3K4me1 deposition in Drosoph...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764455/ https://www.ncbi.nlm.nih.gov/pubmed/36516782 http://dx.doi.org/10.1016/j.celrep.2022.111832 |