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NLRP3 deficiency decreases alcohol intake controlling anxiety-like behavior via modification of glutamatergic transmission in corticostriatal circuits

BACKGROUND: Alcohol use disorders result from repeated binge and chronic alcohol consumption followed by negative effects, such as anxiety, upon cessation. This process is associated with the activation of NLRP3 inflammasome-mediated responses. However, whether and how inhibition of the NLRP3 inflam...

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Detalles Bibliográficos
Autores principales: Li, Ziyi, Vidjro, Olivia Ewi, Guo, Gengni, Du, Yanfeng, Zhou, Yao, Xie, Qian, Li, Jiaxin, Gao, Keqiang, Zhou, Li, Ma, Tengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764485/
https://www.ncbi.nlm.nih.gov/pubmed/36539796
http://dx.doi.org/10.1186/s12974-022-02666-w