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Insufficient HtrA2 causes meiotic defects in aging germinal vesicle oocytes

BACKGROUND: High-temperature requirement protease A2 (HtrA2/Omi) is a mitochondrial chaperone that is highly conserved from bacteria to humans. It plays an important role in mitochondrial homeostasis and apoptosis. In this study, we investigated the role of HtrA2 in mouse oocyte maturation. METHODS:...

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Detalles Bibliográficos
Autores principales: Gao, Min, Qiu, Yanling, Cao, Tianqi, Li, Dungao, Wang, Jingwen, Jiao, Yiren, Chen, Zhiyun, Huang, Junjiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764539/
https://www.ncbi.nlm.nih.gov/pubmed/36539842
http://dx.doi.org/10.1186/s12958-022-01048-4