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Tumor mutation burden involving epigenetic regulatory genes and the RhoA GTPase predicts overall survival in nodal mature T-cell lymphomas

Nodal mature T-cell lymphomas (nMTCL) comprises a heterogeneous group of rare malignancies with aggressive biological behavior and poor prognosis. Epigenetic phenomena, including mutations in genes that control DNA methylation and histone deacetylation, in addition to inactivating mutations in the R...

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Detalles Bibliográficos
Autores principales: de Pádua Covas Lage, Luís Alberto, Culler, Hebert Fabrício, Barreto, Guilherme Carneiro, Reichert, Cadiele Oliana, Levy, Débora, de Oliveira Costa, Renata, Rocha, Vanderson, Pereira, Juliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764541/
https://www.ncbi.nlm.nih.gov/pubmed/36536430
http://dx.doi.org/10.1186/s13148-022-01395-4