Signaling pathways, microenvironment, and targeted treatments in Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) is an inflammatory myeloid malignancy in the “L-group” histiocytosis. Mitogen-activated protein kinase (MAPK) pathway activating mutations are detectable in nearly all LCH lesions. However, the pathogenic roles of MAPK pathway activation in the development of hist...

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Detalles Bibliográficos
Autores principales: Gao, Xue-min, Li, Jian, Cao, Xin-xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764551/
https://www.ncbi.nlm.nih.gov/pubmed/36536400
http://dx.doi.org/10.1186/s12964-022-00917-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764551/
https://www.ncbi.nlm.nih.gov/pubmed/36536400
http://dx.doi.org/10.1186/s12964-022-00917-0

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