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Experience-dependent changes in hippocampal spatial activity and hippocampal circuit function are disrupted in a rat model of Fragile X Syndrome

BACKGROUND: Fragile X syndrome (FXS) is a common single gene cause of intellectual disability and autism spectrum disorder. Cognitive inflexibility is one of the hallmarks of FXS with affected individuals showing extreme difficulty adapting to novel or complex situations. To explore the neural corre...

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Detalles Bibliográficos
Autores principales: Asiminas, Antonis, Booker, Sam A., Dando, Owen R., Kozic, Zrinko, Arkell, Daisy, Inkpen, Felicity H., Sumera, Anna, Akyel, Irem, Kind, Peter C., Wood, Emma R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764562/
https://www.ncbi.nlm.nih.gov/pubmed/36536454
http://dx.doi.org/10.1186/s13229-022-00528-z