SMAD9-MYCN positive feedback loop represents a unique dependency for MYCN-amplified neuroblastoma

BACKGROUND: Neuroblastoma (NB) is the most common extracranial solid tumor occurring during childhood and high-risk NB patients have a poor prognosis. The amplified MYCN gene serves as an important determinant of a high risk of NB. METHODS: We performed an integrative screen using public NB tissue a...

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Detalles Bibliográficos
Autores principales: Tan, Kezhe, Mo, Jialin, Li, Meng, Dong, Yu, Han, Yujie, Sun, Xi, Ma, Yingxuan, Zhu, Kai, Wu, Wei, Lu, Li, Liu, Jiangbin, Zhao, Kewen, Zhang, Lei, Tang, Yujie, Lv, Zhibao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764568/
https://www.ncbi.nlm.nih.gov/pubmed/36539767
http://dx.doi.org/10.1186/s13046-022-02563-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764568/
https://www.ncbi.nlm.nih.gov/pubmed/36539767
http://dx.doi.org/10.1186/s13046-022-02563-3

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