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Single-cell transcriptomics highlights immunological dysregulations of monocytes in the pathobiology of COPD
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a common respiratory disease, whose pathogenetic complexity was strongly associated with aging/smoking and poorly understood. METHODS: Here we performed single-cell RNA sequencing (scRNA-seq) analysis of 66,610 cells from COPD and age-strat...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764587/ https://www.ncbi.nlm.nih.gov/pubmed/36539833 http://dx.doi.org/10.1186/s12931-022-02293-2 |