Single-cell transcriptomics highlights immunological dysregulations of monocytes in the pathobiology of COPD

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a common respiratory disease, whose pathogenetic complexity was strongly associated with aging/smoking and poorly understood. METHODS: Here we performed single-cell RNA sequencing (scRNA-seq) analysis of 66,610 cells from COPD and age-strat...

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Detalles Bibliográficos
Autores principales: Huang, Qiqing, Wang, Yuanyuan, Zhang, Lili, Qian, Wei, Shen, Shaoran, Wang, Jingshen, Wu, Shuangshuang, Xu, Wei, Chen, Bo, Lin, Mingyan, Wu, Jianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764587/
https://www.ncbi.nlm.nih.gov/pubmed/36539833
http://dx.doi.org/10.1186/s12931-022-02293-2

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