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Efficacy and Immune Correlates of OMP-1B and VirB2-4 Vaccines for Protection of Dogs from Tick Transmission of Ehrlichia chaffeensis

Ehrlichia chaffeensis, an obligatory intracellular bacterium, causes human monocytic ehrlichiosis, an emerging disease transmitted by the Lone Star tick, Amblyomma americanum. Here, we investigated the vaccine potential of OMP-1B and VirB2-4. Among the highly expressed and immunodominant E. chaffeen...

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Detalles Bibliográficos
Autores principales: Budachetri, Khemraj, Lin, Mingqun, Chien, Rory C., Zhang, Wenqing, Brock, Guy Nathaniel, Rikihisa, Yasuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765013/
https://www.ncbi.nlm.nih.gov/pubmed/36342170
http://dx.doi.org/10.1128/mbio.02140-22