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Respiratory Syncytial Virus Two-Step Infection Screen Reveals Inhibitors of Early and Late Life Cycle Stages

Human respiratory syncytial virus (hRSV) infection is a leading cause of severe respiratory tract infections. Effective, directly acting antivirals against hRSV are not available. We aimed to discover new and chemically diverse candidates to enrich the hRSV drug development pipeline. We used a two-s...

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Detalles Bibliográficos
Autores principales: Sake, Svenja M., Kosch, Christina, Blockus, Sebastian, Haid, Sibylle, Gunesch, Antonia P., Zhang, Xiaoyu, Friesland, Martina, Trummer, Sofie B., Grethe, Christina, Kühnel, Anne, Rückert, Jessica, Duprex, W. Paul, Huang, Jiabin, Rameix-Welti, Marie-Anne, Empting, Martin, Fischer, Nicole, Hirsch, Anna K. H., Schulz, Thomas F., Pietschmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765014/
https://www.ncbi.nlm.nih.gov/pubmed/36346232
http://dx.doi.org/10.1128/aac.01032-22