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Respiratory Syncytial Virus Two-Step Infection Screen Reveals Inhibitors of Early and Late Life Cycle Stages
Human respiratory syncytial virus (hRSV) infection is a leading cause of severe respiratory tract infections. Effective, directly acting antivirals against hRSV are not available. We aimed to discover new and chemically diverse candidates to enrich the hRSV drug development pipeline. We used a two-s...
Autores principales: | Sake, Svenja M., Kosch, Christina, Blockus, Sebastian, Haid, Sibylle, Gunesch, Antonia P., Zhang, Xiaoyu, Friesland, Martina, Trummer, Sofie B., Grethe, Christina, Kühnel, Anne, Rückert, Jessica, Duprex, W. Paul, Huang, Jiabin, Rameix-Welti, Marie-Anne, Empting, Martin, Fischer, Nicole, Hirsch, Anna K. H., Schulz, Thomas F., Pietschmann, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765014/ https://www.ncbi.nlm.nih.gov/pubmed/36346232 http://dx.doi.org/10.1128/aac.01032-22 |
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