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Longitudinal Analysis of the Microbiome and Metabolome in the 5xfAD Mouse Model of Alzheimer’s Disease

Recent reports implicate gut microbiome dysbiosis in the onset and progression of Alzheimer’s disease (AD), yet studies involving model animals overwhelmingly omit the microbial perspective. Here, we evaluate longitudinal microbiomes and metabolomes from a popular transgenic mouse model for familial...

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Detalles Bibliográficos
Autores principales: Dunham, Sage J. B., McNair, Katelyn A., Adams, Eric D., Avelar-Barragan, Julio, Forner, Stefania, Mapstone, Mark, Whiteson, Katrine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765021/
https://www.ncbi.nlm.nih.gov/pubmed/36468884
http://dx.doi.org/10.1128/mbio.01794-22