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synDNA—a Synthetic DNA Spike-in Method for Absolute Quantification of Shotgun Metagenomic Sequencing

Microbiome studies have the common goal of determining which microbial taxa are present, respond to specific conditions, or promote phenotypic changes in the host. Most of these studies rely on relative abundance measurements to drive conclusions. Inherent limitations of relative values are the inab...

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Detalles Bibliográficos
Autores principales: Zaramela, Livia S., Tjuanta, Megan, Moyne, Oriane, Neal, Maxwell, Zengler, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765022/
https://www.ncbi.nlm.nih.gov/pubmed/36317886
http://dx.doi.org/10.1128/msystems.00447-22