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TaxiBGC: a Taxonomy-Guided Approach for Profiling Experimentally Characterized Microbial Biosynthetic Gene Clusters and Secondary Metabolite Production Potential in Metagenomes

Biosynthetic gene clusters (BGCs) in microbial genomes encode bioactive secondary metabolites (SMs), which can play important roles in microbe-microbe and host-microbe interactions. Given the biological significance of SMs and the current profound interest in the metabolic functions of microbiomes,...

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Detalles Bibliográficos
Autores principales: Gupta, Vinod K., Bakshi, Utpal, Chang, Daniel, Lee, Aileen R., Davis, John M., Chandrasekaran, Sriram, Jin, Yong-Su, Freeman, Michael F., Sung, Jaeyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765181/
https://www.ncbi.nlm.nih.gov/pubmed/36378489
http://dx.doi.org/10.1128/msystems.00925-22