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TaxiBGC: a Taxonomy-Guided Approach for Profiling Experimentally Characterized Microbial Biosynthetic Gene Clusters and Secondary Metabolite Production Potential in Metagenomes
Biosynthetic gene clusters (BGCs) in microbial genomes encode bioactive secondary metabolites (SMs), which can play important roles in microbe-microbe and host-microbe interactions. Given the biological significance of SMs and the current profound interest in the metabolic functions of microbiomes,...
Autores principales: | Gupta, Vinod K., Bakshi, Utpal, Chang, Daniel, Lee, Aileen R., Davis, John M., Chandrasekaran, Sriram, Jin, Yong-Su, Freeman, Michael F., Sung, Jaeyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765181/ https://www.ncbi.nlm.nih.gov/pubmed/36378489 http://dx.doi.org/10.1128/msystems.00925-22 |
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