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Systematic Metabolic Profiling Identifies De Novo Sphingolipid Synthesis as Hypha Associated and Essential for Candida albicans Filamentation
The yeast-to-hypha transition is a key virulence attribute of the opportunistic human fungal pathogen Candida albicans, since it is closely tied to infection-associated processes such as tissue invasion and escape from phagocytes. While the nature of hypha-associated gene expression required for fun...
Autores principales: | Garbe, Enrico, Gerwien, Franziska, Driesch, Dominik, Müller, Tina, Böttcher, Bettina, Gräler, Markus, Vylkova, Slavena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765226/ https://www.ncbi.nlm.nih.gov/pubmed/36264075 http://dx.doi.org/10.1128/msystems.00539-22 |
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