Systematic Metabolic Profiling Identifies De Novo Sphingolipid Synthesis as Hypha Associated and Essential for Candida albicans Filamentation

The yeast-to-hypha transition is a key virulence attribute of the opportunistic human fungal pathogen Candida albicans, since it is closely tied to infection-associated processes such as tissue invasion and escape from phagocytes. While the nature of hypha-associated gene expression required for fun...

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Detalles Bibliográficos
Autores principales: Garbe, Enrico, Gerwien, Franziska, Driesch, Dominik, Müller, Tina, Böttcher, Bettina, Gräler, Markus, Vylkova, Slavena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765226/
https://www.ncbi.nlm.nih.gov/pubmed/36264075
http://dx.doi.org/10.1128/msystems.00539-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765226/
https://www.ncbi.nlm.nih.gov/pubmed/36264075
http://dx.doi.org/10.1128/msystems.00539-22

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