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Single-cell RNA sequencing combined with single-cell proteomics identifies the metabolic adaptation of islet cell subpopulations to high-fat diet in mice

AIMS/HYPOTHESIS: Islets have complex heterogeneity and subpopulations. Cell surface markers representing alpha, beta and delta cell subpopulations are urgently needed for investigations to explore the compositional changes of each subpopulation in obesity progress and diabetes onset, and the adaptat...

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Detalles Bibliográficos
Autores principales: Fu, Qi, Jiang, Hemin, Qian, Yu, Lv, Hui, Dai, Hao, Zhou, Yuncai, Chen, Yang, He, Yunqiang, Gao, Rui, Zheng, Shuai, Liang, Yucheng, Li, Siqi, Xu, Xinyu, Xu, Kuanfeng, Yang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765371/
https://www.ncbi.nlm.nih.gov/pubmed/36538064
http://dx.doi.org/10.1007/s00125-022-05849-5