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Human Cytomegalovirus pUL11, a CD45 Ligand, Disrupts CD4 T Cell Control of Viral Spread in Epithelial Cells

Human cytomegalovirus (HCMV) encodes numerous immunomodulatory genes that facilitate its persistence. Previously described mechanisms by which HCMV avoids T cell control typically involve evasion of detection by infected cells. Here, we show that the virus also inhibits T cells directly via an inter...

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Detalles Bibliográficos
Autores principales: Osanyinlusi, Samuel A., Zischke, Jasmin, Jacobs, Roland, Weissinger, Eva M., Schulz, Thomas F., Kay-Fedorov, Penelope C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765415/
https://www.ncbi.nlm.nih.gov/pubmed/36445084
http://dx.doi.org/10.1128/mbio.02946-22