Directed Evolution Detects Supernumerary Centric Chromosomes Conferring Resistance to Azoles in Candida auris

Candida auris exhibits resistance to multiple antifungal drug classes and sterilization agents, posing threats to the immunocompromised worldwide. Among the four major geographical clades, the East Asian clade 2 isolates of C. auris are mostly drug susceptible. In this study, we experimentally evolv...

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Detalles Bibliográficos
Autores principales: Narayanan, Aswathy, Kumar, Praveen, Chauhan, Anshu, Kumar, Mohit, Yadav, Kusum, Banerjee, Atanu, Sharma, Ravi Datta, Rudramurthy, Shivaprakash M., Chakrabarti, Arunaloke, Sanyal, Kaustuv, Prasad, Rajendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765433/
https://www.ncbi.nlm.nih.gov/pubmed/36445083
http://dx.doi.org/10.1128/mbio.03052-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765433/
https://www.ncbi.nlm.nih.gov/pubmed/36445083
http://dx.doi.org/10.1128/mbio.03052-22

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