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Origin and Dynamics of Mycobacterium tuberculosis Subpopulations That Predictably Generate Drug Tolerance and Resistance

Initial responses to tuberculosis treatment are poor predictors of final therapeutic outcomes in drug-susceptible disease, suggesting that treatment success depends on features that are hidden within a small minority of the overall infecting Mycobacterium tuberculosis population. We developed a mult...

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Detalles Bibliográficos
Autores principales: Sebastian, Jees, Thomas, Anooja, Levine, Carly, Shrestha, Riju, Levy, Shawn, Safi, Hassan, Pentakota, Sri Ram, Kumar, Pradeep, Alland, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765434/
https://www.ncbi.nlm.nih.gov/pubmed/36346244
http://dx.doi.org/10.1128/mbio.02795-22