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Caspase-Mediated Regulation and Cellular Heterogeneity of the cGAS/STING Pathway in Kaposi’s Sarcoma-Associated Herpesvirus Infection

As a result of the ongoing virus-host arms race, viruses have evolved numerous immune subversion strategies, many of which are aimed at suppressing the production of type I interferons (IFNs). Apoptotic caspases have recently emerged as important regulators of type I IFN signaling both in noninfecti...

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Detalles Bibliográficos
Autores principales: Tabtieng, Tate, Lent, Rachel C., Kaku, Machika, Monago Sanchez, Alvaro, Gaglia, Marta Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765453/
https://www.ncbi.nlm.nih.gov/pubmed/36255240
http://dx.doi.org/10.1128/mbio.02446-22