Cargando…

HPV-16 E7 Interacts with the Endocytic Machinery via the AP2 Adaptor μ2 Subunit

Human papillomavirus (HPV) E7 plays a major role in HPV-induced malignancy, perturbing cell cycle regulation, and driving cell proliferation. Major targets of cancer-causing HPV E7 proteins are the pRB family of tumor suppressors, which E7 targets for proteasome-mediated degradation and whose intera...

Descripción completa

Detalles Bibliográficos
Autores principales: Basukala, Om, Trejo-Cerro, Oscar, Myers, Michael P., Pim, David, Massimi, Paola, Thomas, Miranda, Guarnaccia, Corrado, Owen, David, Banks, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765456/
https://www.ncbi.nlm.nih.gov/pubmed/36255238
http://dx.doi.org/10.1128/mbio.02302-22