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HPV-16 E7 Interacts with the Endocytic Machinery via the AP2 Adaptor μ2 Subunit
Human papillomavirus (HPV) E7 plays a major role in HPV-induced malignancy, perturbing cell cycle regulation, and driving cell proliferation. Major targets of cancer-causing HPV E7 proteins are the pRB family of tumor suppressors, which E7 targets for proteasome-mediated degradation and whose intera...
Autores principales: | Basukala, Om, Trejo-Cerro, Oscar, Myers, Michael P., Pim, David, Massimi, Paola, Thomas, Miranda, Guarnaccia, Corrado, Owen, David, Banks, Lawrence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765456/ https://www.ncbi.nlm.nih.gov/pubmed/36255238 http://dx.doi.org/10.1128/mbio.02302-22 |
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