Haemophilus ducreyi Infection Induces Oxidative Stress, Central Metabolic Changes, and a Mixed Pro- and Anti-inflammatory Environment in the Human Host

Few studies have investigated host-bacterial interactions at sites of infection in humans using transcriptomics and metabolomics. Haemophilus ducreyi causes cutaneous ulcers in children and the genital ulcer disease chancroid in adults. We developed a human challenge model in which healthy adult vol...

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Detalles Bibliográficos
Autores principales: Brothwell, Julie A., Fortney, Kate R., Gao, Hongyu, Wilson, Landon S., Andrews, Caroline F., Tran, Tuan M., Hu, Xin, Batteiger, Teresa A., Barnes, Stephen, Liu, Yunlong, Spinola, Stanley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765465/
https://www.ncbi.nlm.nih.gov/pubmed/36453940
http://dx.doi.org/10.1128/mbio.03125-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765465/
https://www.ncbi.nlm.nih.gov/pubmed/36453940
http://dx.doi.org/10.1128/mbio.03125-22

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