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Haemophilus ducreyi Infection Induces Oxidative Stress, Central Metabolic Changes, and a Mixed Pro- and Anti-inflammatory Environment in the Human Host
Few studies have investigated host-bacterial interactions at sites of infection in humans using transcriptomics and metabolomics. Haemophilus ducreyi causes cutaneous ulcers in children and the genital ulcer disease chancroid in adults. We developed a human challenge model in which healthy adult vol...
Autores principales: | Brothwell, Julie A., Fortney, Kate R., Gao, Hongyu, Wilson, Landon S., Andrews, Caroline F., Tran, Tuan M., Hu, Xin, Batteiger, Teresa A., Barnes, Stephen, Liu, Yunlong, Spinola, Stanley M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765465/ https://www.ncbi.nlm.nih.gov/pubmed/36453940 http://dx.doi.org/10.1128/mbio.03125-22 |
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