Structural Foundations of Potassium Selectivity in Channelrhodopsins

Potassium-selective channelrhodopsins (KCRs) are light-gated K(+) channels recently found in the stramenopile protist Hyphochytrium catenoides. When expressed in neurons, KCRs enable high-precision optical inhibition of spiking (optogenetic silencing). KCRs are capable of discriminating K(+) from Na...

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Detalles Bibliográficos
Autores principales: Govorunova, Elena G., Sineshchekov, Oleg A., Brown, Leonid S., Bondar, Ana-Nicoleta, Spudich, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765531/
https://www.ncbi.nlm.nih.gov/pubmed/36413022
http://dx.doi.org/10.1128/mbio.03039-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765531/
https://www.ncbi.nlm.nih.gov/pubmed/36413022
http://dx.doi.org/10.1128/mbio.03039-22

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