Antagonism of the Azoles to Olorofim and Cross-Resistance Are Governed by Linked Transcriptional Networks in Aspergillus fumigatus

Aspergillosis, in its various manifestations, is a major cause of morbidity and mortality. Very few classes of antifungal drugs have been approved for clinical use to treat these diseases and resistance to the first-line therapeutic class, the triazoles are increasing. A new class of antifungals tha...

Descripción completa

Detalles Bibliográficos
Autores principales: van Rhijn, Norman, Hemmings, Sam, Storer, Isabelle S. R., Valero, Clara, Bin Shuraym, Hajer, Goldman, Gustavo H., Gsaller, Fabio, Amich, Jorge, Bromley, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765627/
https://www.ncbi.nlm.nih.gov/pubmed/36286521
http://dx.doi.org/10.1128/mbio.02215-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765627/
https://www.ncbi.nlm.nih.gov/pubmed/36286521
http://dx.doi.org/10.1128/mbio.02215-22

Ejemplares similares