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A Persistent Tuberculosis Outbreak in the UK Is Characterized by Hydrophobic fadB4-Deficient Mycobacterium tuberculosis That Replicates Rapidly in Macrophages

The genetic diversity of Mycobacterium tuberculosis can influence disease severity and transmissibility. To better understand how this diversity influences individuals and communities, we phenotyped M. tuberculosis that was causing a persistent outbreak in the East Midlands, United Kingdom. Compared...

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Detalles Bibliográficos
Autores principales: Farzand, Robeena, Haigh, Richard D., Monk, Philip, Haldar, Pranabashis, Patel, Hemu, Pareek, Manish, Verma, Raman, Barer, Michael R., Woltmann, Gerrit, Ahyow, Lauren, Jagatia, Heena, Decker, Jonathan, Mukamolova, Galina V., Cooper, Andrea M., Garton, Natalie J., O’Hare, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765663/
https://www.ncbi.nlm.nih.gov/pubmed/36374090
http://dx.doi.org/10.1128/mbio.02656-22