VSGs Expressed during Natural T. b. gambiense Infection Exhibit Extensive Sequence Divergence and a Subspecies-Specific Bias towards Type B N-Terminal Domains

Trypanosoma brucei gambiense is the primary causative agent of human African trypanosomiasis (HAT), a vector-borne disease endemic to West and Central Africa. The extracellular parasite evades antibody recognition within the host bloodstream by altering its variant surface glycoprotein (VSG) coat th...

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Detalles Bibliográficos
Autores principales: So, Jaime, Sudlow, Sarah, Sayeed, Abeer, Grudda, Tanner, Deborggraeve, Stijn, Ngoyi, Dieudonné Mumba, Desamber, Didier Kashiama, Wickstead, Bill, Lejon, Veerle, Mugnier, Monica R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765701/
https://www.ncbi.nlm.nih.gov/pubmed/36354333
http://dx.doi.org/10.1128/mbio.02553-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765701/
https://www.ncbi.nlm.nih.gov/pubmed/36354333
http://dx.doi.org/10.1128/mbio.02553-22

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