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TCA and SSRI Antidepressants Exert Selection Pressure for Efflux-Dependent Antibiotic Resistance Mechanisms in Escherichia coli

Microbial diversity is reduced in the gut microbiota of animals and humans treated with selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs). The mechanisms driving the changes in microbial composition, while largely unknown, is critical to understand considering that...

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Detalles Bibliográficos
Autores principales: Ou, Jin, Elizalde, Paul, Guo, Hao-Bo, Qin, Hong, Tobe, Brian T.D., Choy, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765716/
https://www.ncbi.nlm.nih.gov/pubmed/36374097
http://dx.doi.org/10.1128/mbio.02191-22