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Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression

One of the central challenges for cancer therapy is the identification of factors in the tumor microenvironment that increase tumor progression and immune tolerance. In breast cancer, fibrosis is a histopathologic criterion for invasive cancer and poor survival that results from inflammatory factors...

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Detalles Bibliográficos
Autores principales: Yuan, Hongyan, Jin, Lu, Xiang, Handan, Bhattacharya, Anannya, Brandish, Philip E., Baltus, Gretchen, Tong, Alexander, Zhou, Changyan, Glazer, Robert I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765860/
https://www.ncbi.nlm.nih.gov/pubmed/36537914
http://dx.doi.org/10.18632/oncotarget.28330